Dr. Supratim Mandal

Assistant Professor

Department: Department of Microbiology
Phone Number: +91-9874883540
Institutional E-Mail: supratimmicro19@klyuniv.ac.in
Web URL: https://smlabkumicro.wixsite.com/mylab
Educational Qualifications:

1. Ph.D. in Cancer Immunology
Department of Zoology , West Bengal State University, Barasat, India
2. UGC-CSIR Junior Research Fellow
Department of Infectious diseases & Immunology, Indian Institute of Chemical Biology, Kolkata.
3. M.Sc. in Microbiology: 2007
Department of Microbiology, Calcutta University, Kolkata, India
4. B.Sc. in Microbiology: 2005
Calcutta University, Kolkata, India

Awards and Honours (National/International)

• Awarded International Travel Fellowship for paper presentation at Pathobiology for Investigators, Students & Academians (PISA) 2017
conference organized by the American Society for Investigative Pathology (ASIP); September 25-27, 2017, at University of Pittsburgh, PA, USA.
• Awarded Junior Research Fellowship, Council of Scientific and Industrial Research, Government of India, June 2007 (CSIR/NET).
• Qualified graduate aptitude test in engineering (GATE) in life sciences (2007) under Department of Secondary and Higher Education, Ministry of
Human Resource Development, Government of India.

Collaborative Programs

1. Scientific and Academic Collaboration with Amity Institute of Molecular Medicine and Stem Cell Research (AIMMSCR), Amity University, J3, Sector
125, Noida 201303, UP.
2. Scientific Collaboration with Department of Botany, University of Calcutta, Calcutta, West Bengal.
3. Scientific Collaboration with Department of Chemistry, Acharya Prafulla Chandra College, Kolkata.
4. Scientific Collaboration with Department of Pharmaceutical Sciences, JIS school of Pharmacy, Kolkata.

Research Area:

1. Isolation, identification and characterization of novel natural compounds for the treatment of microbial infections.
2. Understanding the molecular mechanism of development and progression of microbial biofilms and development of possible drug candidates for
for their removal.
3. Development of multiple signal modulation therapy of cancer: A mechanistic approach to induce apoptosis and retard metastasis.
4. Understanding the life cycle of the pathogenic micro-organisms with special emphasis on molecular and immunological details of their
pathogenesis and development of convenient therapy.
5. Synthesis of heavy metal conjugated nanoparticles and improved drug delivery systems for overcoming antibacterial resistance.

Teaching Experience:

1. Assistant Professor : July, 2018- Till date.
Department of Microbiology,
University of Kalyani, Kalyani, Nadia.
2. Assistant Professor : April, 2010 – July, 2018
Department of Microbiology,
Acharya Prafulla Chandra College, Kolkata.

Administrative Experiences

1. Member, Departmental Research Committee.
2. Member, Post Graduate Board of Studies, University of Kalyani.
3. Member, Academic and Administrative Departments for All India Survey on Higher Education (AISHE) committee, University of Kalyani.
4. Member, Committee for Webinars and Scientific Lecture Series, University of Kalyani.

List of Publications(Peer-Reviewed)

1. Human microbial dysbiosis as driver of gynecological malignancies. Mandal S, Bandyopadhyay S, Tyagi K, Roy A. Biochimie. 2022 Feb 14;197:86-95.
(Impact Factor 4).
2. Recent advances in understanding the molecular role of phosphoinositide-specific phospholipase C gamma 1 as an emerging onco-driver and
novel therapeutic target in human carcinogenesis.
Mandal S, Bandyopadhyay S, Tyagi K, Roy A. Biochim Biophys Acta Rev Cancer. 2021 Dec;1876(2):188619. (Impact Factor 10.68)
3. A trinuclear Zn(II) Schiff base azido compound: synthesis, structure and exploration of antimicrobial activity.
Ghosh M, Biswas S, Roy M, Biswas S, Ghosh P, Koner S, Mandal S and Saha S. New J. Chem., 2021,45, 12296-12304. (Impact Factor 3.59)
4. Recent advancements in therapeutic targeting of the Warburg effect in refractory ovarian cancer: A promise towards disease remission.
Tyagi K, Mandal S, Roy A. Biochim Biophys Acta Rev Cancer. 2021 Aug;1876(1):188563. (Impact Factor 10.68)
5. Role of Alarmone in Biofilm Development: A Weapon to Survive Under Stress.
Shrabasti Bandyopadhyay, Samik Biswas, Nikhil Chandra Halder and Supratim Mandal. 2022 January. 09.01.020. (Impact Factor 4.675)
6. Combination of Mycobacterium indicus pranii and Heat-Induced Promastigotes Cures Drug-Resistant Leishmania Infection: Critical Role of
Interleukin-6-Producing Classical Dendritic Cells. Dey S, Mukherjee D, Sultana SS, Mallick S, Dutta A, Ghosh J, Hussain A, Sarkar B, Mandal S, Patra
P, Saha B, Pal C. Infect Immun. 2020 May 20;88(6):e00222-19. (Impact Factor 3.25)
7. Induction of ROS by a novel chromone linked nitrone derivative promotes mitochondria mediated caspase dependent apoptosis in HepG2 and HeLa
cells. Mandal S, Mallick S, Maiti S, Bandyopadhyay C, Pal C. World Scientific News. 2018 July WSN 103 (2018) 178-196.
8. Induction of apoptosis by zerumbone isolated from Zingiber zerumbet (L.) Smith in protozoan parasite Leishmania donovani due to oxidative
stress. Mukherjee D, Singh CB, Dey S, Mandal S, Ghosh J, Mallick S, Hussain A, Swapana N, Ross SA, Pal C. Brazilian Journal Of Infectious Disease.
Jan-Feb 2016;20(1):48-55. (Impact Factor 2)
9. A novel triterpene from Astraeus hygrometricus induces reactive oxygen species leading to death in Leishmaniadonovani. Mallick S, DeyS, Mandal
S, Dutta A, Mukherjee D, Biswas G, Chatterjee S, Mallick S, Lai TK, Acharya K, Pal C. Future Microbiology. 2015;10(5):763-89. (Impact Factor 3.2)
10. Synthesis and biological evaluation of ferrocenylquinoline as a potential antileishmanialagent.Yousuf M, Mukherjee D, Pal A, Dey S, Mandal S, Pal
C, Adhikari S. ChemMedChem. 2015 Mar;10(3):546-54. (Impact Factor 3.2)
11. Selective inhibition of Leishmania donovani by active extracts of wild mushrooms used by the tribal population of India: An in vitro exploration for
new leads against parasitic protozoans. Mallick S, Dutta A, Dey S, Ghosh J, Mukherjee D,SultanaSS, Mandal S, Paloi S, Khatua S, Acharya K, Pal
Experimental Parasitoloy. 2014 Mar;138:9-17. (Impact Factor 1.8)

Books Published / Book Chapters

Books:
1. “Microbes and Sustainable Development”. (2021) A textbook for Post Graduate Students in Microbiology and NET aspirants in Life Sciences Published by Nectar Publications, Kolkata .
2.
Book Chapters:
1. “Marine Microorganisms: New Frontier in Antimicrobial Therapeutics” for the book “Recent Trends and The Future of Antimicrobial Agents” to
Bentham Science Publishers, Singapore.

Invited Lecture / Session Chaired

• Invited resource person at seven-day workshop on “Drinking water quality analysis with relation to public health” organized by Department of Microbiology, University of Kalyani on 26.03. 2022.
• Invited lecture at National Conference on “Stress Response and Diseases” organized by Department of Biochemistry and Biophysics, University of Kalyani, 6-7 March, 2020.
• Invited resource person at scientific webinar on “Claws of Covid” organized by Department of Microbiology of St Paul’s C.M College, on 10.08.2020.
• Poster: “A novel fungal triterpene induces cell death in Leishmania donovani parasites”.”Mallick S, Dey S, Mandal S, Dutta A, Mukherjee D, Biswas G, Chatterjee S, Mallick S, Lai TK, Acharya K, Pal C of the poster that was presented in the UGC sponsored national level seminar on “Rediscovering 100 years of journey on the field of Immunology: present status of innunological research in India” organized by Department of life Science and Biotechnology, Jadavpur University, September 19 & 20,2011.
• Delivered lecture in National conference on CME in Immunology sponsored by the Department of Biotechnology,Govt. Of India at West Bengal State University, November 4 & 5, 2011.
• Poster: “A novel triterpene from Astraeus hygrometricus induces ROS leading to caspase independent cell death in Leishmania donovani. ”.”Mallick S, DeyS, Mandal S, Dutta A, Mukherjee D, Biswas G, Chatterjee S, Mallick S, Lai TK, Acharya K, Pal C of the poster that was presented and won the best poster award in the International Conference on “Molecular Biology and its applications” organized by Department of life Science and Biotechnology, Jadavpur University, Feb 14 & Feb 15,2014.
• Poster: “Novel triterpenes from fungal species found in rural bengal promises potent thereautic potential against the protozoan parasite Leishmania donovani.”.”Mallick S, DeyS, Mandal S, Dutta A, Mukherjee D, Biswas G, Chatterjee S, Mallick S, Lai TK, Acharya K, Pal C accepted for presentation in National Conference on “ Advanced Biology through Technology and computation” organized by Dept. of Microbiology, West Bengal State University, August 22, 2014.
• Poster:“Mycobacterium indicuspranii (Mw) in combination with heat induced promastigotes persuade host protection against Leishmania donovani infection: Activation of IL-6 producing CD11c+ cDC and induction of CXCL10”.DeyS, Mukherjee D,Sultana SS ,Mallick S, Mandal S, Dutta A, Saha B, Pal C of the poster that was presented on National Symposium on Frontiers in Modern Biology, organized by Dept. of Biological Sciences, IISER-Kolkata, Dec 5 & Dec 6,2015.

Membership of Learned Societies

1. Member, American Society for Investigative Pathology.
2. Member, European Society for Medical Oncology.
3. Life Member, Indian Science Congress Association.

ORCID ID https://orcid.org/0000-0003-2603-317X
SCOPUS ID https://www.scopus.com/authid/detail.uri?authorId=56026690900
Google Scholar ID https://scholar.google.com/citations?hl=en&view_op=list_works&gmla=AJsN-F5jq7A6IOo765o9HDJykBLJcBminYmx2QuPUg9Rav6Z97GubP14i7uGV1BQ6BcmUdhJ-u6K8gbEjeS8K2iByxv7PcMd0g&user=Jd_aJHEAAAAJ
Research Supervision

Three students currently pursuing their doctoral degree.