Lakshmishri Lahiry

Lakshmishri Lahiry

Lakshmishri Lahiry

Lakshmishri Lahiry

Department: Department of Physiology
Phone Number: 9432361329
Institutional E-Mail: llahiry@klyuniv.ac.in
Web URL: na
Educational Qualifications:

Ph.D. Science (Life Science and Biotechnology) Jadavpur University (Research at Bose Institute )Kolkata – 2007
M.Sc. Physiology, University of Calcutta – 2001
B.Sc. Physiology, University of Calcutta -1999

Awards and Honours (National/International)

DBT Postdoctoral Research Associateship 2009, Department of Biotechnology, Govt.of India

Research Area:

Current Research focus: Effects of Endocrine Disruptor Chemicals on Reproductive physiology and Cancer.
Broad Field of Research : Cancer and Chemoprevention, Cell Signaling, Tumor Immunology, Cancer Migration and Metastasis, Cancer Stem cell biology and differentiation

Teaching Experience:

PG Teaching (M.Sc) for 10 years – till date, University of Kalyani, Department of Physiology (April 2012 – till date)
UG Teaching (B.Sc) Physiology- 6 months

List of Publications(Peer-Reviewed)

1. Roy A, Lahiry L, Banerjee D, Ghosh M, Banerjee S. Increased Cytoplasmic Localization of p27(kip1) and Its Modulation of RhoA Activity during Progression of Chronic Myeloid Leukemia. PLoS One. 2013 Oct 1;8(10):e76527. (eISSN-1932-6203)
[Impact factor: 4.24]

2. Saha B, Adhikary A, Ray P, Saha S, Chakraborty S, Mohanty S, Das K, Mukherjee S, Mazumdar M, Lahiry L, Hossain S, Sa G and Das T. Restoration of tumor suppressor p53 by differentially regulating pro- and anti-p53 networks in HPV-18-infected cervical cancer cells. Oncogene 2012; 31(2): 173-86. Publisher : nature publishing group [Impact factor: 8.559]

3. Lahiry L, Saha B, Chakraborty J, Adhikary A, Banerjee S, Das K, Sa G and Das T. Theaflavins target Fas/caspase-8 and Akt/pBad pathways to induce apoptosis in p53-mutated human breast cancer cells. Carcinogenesis 2010; 31(2): 259-68. Publisher : Oxford [Impact factor: 5.402]

4. Adhikary A, Mohanty S, Lahiry L, Hossain S, Chakraborty S and Tanya Das. Theaflavins retard human breast cancer cell migration by inhibiting NF-kappa B via p53-dependent ROSgeneration. FEBS Letters 2010; 584(1): 7-14. Publisher : Elsevier [Impact factor: 3.601]

5. Lahiry L, Saha B, Chakraborty J, Bhattacharyya S, Chattopadhyay S, Banerjee S, Choudhuri T, Mandal D, Bhattacharyya A, Sa G, Das T. Contribution of p53-mediated Bax transactivation in theaflavin-induced mammary epithelial carcinoma cell apoptosis. Apoptosis 2008; 13: 771-781. Publisher : Springer [Impact factor: 4.397]

6. Bhattacharyya S, Mandal D, Sen G S, Pal S, Banerjee S, Lahiry L, Finke J H, Tannwenbaum C S, Das T, Sa G. Tumor-induced oxidative stress perturbs nuclear factor-β activity-augmenting tumor necrosis factor-α-mediatede T-cell death: protection by curcumin. Cancer Res. 2007; 67: 1-9. Publisher : American Association for Cancer Research [Impact factor: 8.234]

7. Mandal D, Bhattacharyya S, Lahiry L, Chattopadhyay S, Sa G, Das T. Black tea-induced decrease in IL-10 and TGF-β of tumor cells promotes Th1/Tc1 response in tumor bearer. Nutrition and Cancer 2007; 58: 213-221. Publisher: Routledge [Impact factor: 2.553]

8. Bhattacharyya A, Mandal D, Lahiry L, Bhattacharyya S, Chattopadhyay S, Ghosh U, Sa G, Das T. Black tea-induced amelioration of hepatic oxidative stress through antioxidative activity in EAC-bearing mice. J Environ Pathol Toxicol Oncol. 2007; 26 (4):245-254. Publisher : begellhouse [Impact factor: 1.066]

9. Mandal D, Lahiry L, Bhattacharyya A, Bhattacharyya S, Sa G, Das T. Tumor-induced thymic involution via Inhibition of IL-7R and its JAK-STAT signaling pathway: Protection by Black Tea. Int. Immunopharmacology. 2006; 6: 433-44a. Publisher : Elsevier [Impact factor: 2.325]

10. Bhattacharyya A, Lahiry L, Mandal D, Sa G, Das T. Black tea induces tumor cell apoptosis by Bax translocation, loss in mitochondrial transmembrane potential, cytochrome c release and caspase activation. Int J Cancer. 2005; 117:308-15. Publisher : Wiley [Impact factor: 4.926]

11. Mandal D, Lahiry L, Bhattacharyya A, Chattopadhyay S, Siddiqi M, Sa G, Das T. Black tea protects thymocytes in tumor-bearing animals by differential regulation of intracellular ROS in tumor cells and thymocytes. J Environ Pathol Toxicol Oncol. 2005; 24:91-104. Publisher : begellhouse [Impact factor: 1.066]

12. Mandal D, Bhattacharyya A, Lahiry L, Choudhuri T, Sa G and Das T. Failure in peripheral immunosurveillance due to thymic atrophy: Importance of thymocyte maturation and apoptosis in adult tumor bearer. Life Sci. 2005;77: 2703-16. Publisher : Elsevier [Impact factor: 2.672]

13. Bhattacharyya A, Mandal D, Lahiry L, Sa G, Das T. Black tea protects immunocytes from tumor-induced apoptosis by changing Bcl-2/Bax ratio. Cancer Lett. 2004; 209:147-54. Publisher : Elsevier [Impact factor: 4.864]

14. Mandal D, Lahiry L, Bhattacharyya A, Bhattacharyya A, Sa G & Das T. Apoptogenic Effect of Black Tea on Ehrlich’s Ascites Carcinoma: Evidence for Reduced Toxicity and Enhanced Immunity in Tumor-bearer. Int J Tea Sci 2004; 3: 261-272.

Books Published / Book Chapters

Lahiry L, Mandal D, Bhattacharyya A, Sa G & Das T. Cancer prevention by cancer regression and rejuvenation of host defense system: Dual role of tea.: Medicinal Properties of TEA (Eds. B Banerjee & TC Chaudhury) Oxford & IBH Publishing Co. Pvt.Ltd. New Delhi 2005: Chapter 7: 89-112.

Also published in Tea Therapeutics (Eds. B Banerjee & TC Chaudhury) Science Publishers Inc., New Hampshire, USA. (2005)

Invited Lecture / Session Chaired

1. National Conference on Sustainable Health Science for Future Generations held at University of Kalyani, 28th-29th April, 2022.
2. 100th Indian Science Congress held at Kolkata, January 3-8, 20013

Details of Extra Mural Research Funding

Sl. No Grant Agency Title of The Project Duration / Tenure Total Cost of The Project
1

UGC

Explicating the role of Mammalian Ste-Kinase (Mst) pathway in Leukemia

2014 -2016

Rs 6,00,000

Membership of Learned Societies

Life member of The Indian Science Congress Association from 2010

Research Supervision

Ph.D Supervisor ; 01 scholar registered in Department of Physiology, University of Kalyani