Swagata Ghosh

Swagata Ghosh

Swagata Ghosh

Swagata Ghosh

Department: Department of Molecular Biology and Biotechnology
Phone Number: 8527127417
Institutional E-Mail: sgmbbtku@klyuniv.ac.in
Educational Qualifications:

1. CSIR Pool Scientist, NIPGR, New Delhi.

2. Ph.D.: Laboratory of Prof. Asis Datta, Centre of Molecular Medicine, Jawaharlal Nehru University, New Delhi.

3. Post M.Sc. Research Experience: Chittaranjan National Cancer Institute, Laboratory of Prof. Ramdas Chatterjee (Viral Associated Human Cancer)

4. M.Sc. (Botany, Spl Paper: Cell Biology and Molecular Genetics) : 1st Class (2nd rank), University of Calcutta.

5. B.Sc. (Botany Honours) : 1st Class, Presidency College, University of Calcutta.

Awards and Honours (National/International)

Early Career Research Award from DST-SERB.

Research Area:

Cell and Molecular Biology

Teaching Experience:

8 years

List of Publications(Peer-Reviewed)

1. N-acetylglucosamine kinase, Hxk1is a multifaceted metabolic enzyme in model pathogenic yeast Candida albicans. Hanumantha Rao K, Paul S, Natarajan K, Ghosh S*.Microbiological Research. 2022. 127146.
2. Srg1, a putative protein phosphatase from the HAD family, is involved in stress adaptation in Candida albicans. KH Rao, K Roy, S Ghosh *. Biochimica et Biophysica Acta (BBA)-General Subjects. 2022. 1866 (8), 130164.
3. N-acetylglucosamine transporter, Ngt1, undergoes sugar-responsive endosomal trafficking in Candida albicans.Kongara HR, Roy K, Paul S, Ghosh S*. Mol Microbiol. 2021 Dec 7. doi: 10.1111/mmi.14857.
4. N-acetylglucosamine Signaling: Transcriptional Dynamics of a Novel Sugar Sensing Cascade in a Model Pathogenic Yeast, Candida albicans. Hanumantha Rao K, Paul S, Ghosh S*. J Fungi (Basel). 2021 Jan 19;7(1):65. doi: 10.3390/jof7010065.
5. Sugar Responsive Ubiquitylation mediated Endosomal Trafficking of N‐acetylglucosamine Transporter (Ngt1) in Candida albicans. (Conference Proceeding)KH Rao, S Ghosh*. 2020 The FASEB Journal 34 (S1), 1-1
6. A Haloacid Dehalogenase of Candida albicans: An uncharted territory (Conference Proceeding) S Ghosh*, KH Rao 2018. The FASEB Journal 32, lb137-lb137.
7. Cloning, expression, purification and crystallization of a novel GlcNAc metabolic protein, gig2 (duf1479) from pathogenic fungus Candida albicans .P Rani, G Gautam, KH Rao, S Ghosh*, S Gourinath, SK Dhar, A Datta. 2017.Proteomics Society, India (PSI).
8. Env7p associates with the Golgin protein Imh1 at Trans-Golgi network in Candida albicans. Kongara Hanumantha Rao†., Swagata Ghosh†* and Asis Datta. 2016. mSphere. 3;1(4).
9. N-acetylglucosamine kinase, HXK1 contributes to White-Opaque morphological transition in Candida albicans. Kongara Hanumantha Rao, Deepa Ruhela, Swagata Ghosh*, M. Z. Abdin, Asis Datta.2014 Biochem Biophys Res Commun. 28;445(1):138-144.
10. N-acetylglucosamine (GlcNAc) inducible gene, GIG2, is a novel component of GlcNAc metabolism in Candida albicans. Swagata Ghosh†*, Kongara Hanumantha Rao†, Neel Sarovar Bhavesh, Gobardhan Das,Ved Prakash Dwivedi, and Asis Datta. 2014 Eukaryot Cell. 13(1): 66-76.
11. N-acetylglucosamine kinase, HXK1 is involved in morphogenetic transition and metabolic gene expression in Candida albicans. Kongara Hanumantha Rao†, Swagata Ghosh†*, K. Natarajan and Asis Datta. 2013. PLoS One. 8(1).
12. Swagata Ghosh†*, Kongara Hanumantha Rao†, Manjistha Sengupta, Sujt K Bhattacharya and Asis Datta. 2011. Two gene clusters co-ordinate for a functional N-acetylglucosamine catabolic pathway in Vibrio cholerae. Molecular Microbiology. 80: 6,1549–1560. (This work was featured in Global Medical Discovery).

Details of Extra Mural Research Funding

Sl. No Grant Agency Title of The Project Duration / Tenure Total Cost of The Project
1

WBHEST

Dissecting the molecular mechanism of N-acetylglucosamine utilization in C. albicans for a targeted drug therapy

3 years

18,99,999/-

2

DST-SERB

Genome-wide protein-DNA binding dynamics and protein interaction studies to understand sugar specific responses of a transcription factor in the model prokaryotic pathogen Vibrio cholerae.

3 Years

54,99,999/-

Patents

Patent 1: Recombinant microorganisms and uses thereof. US Patent US 13/451,481. Granted. Publication number: US8734814 B2. Asis Datta, Swagata Ghosh, K. Hanumantha Rao.
Patent 2: Mutant microorganisms and uses thereof. Indian Patent 622/DEL/2012. Asis Datta, Swagata Ghosh, K. Hanumantha Rao.

ORCID ID 0000-0003-3911-6927
Google Scholar ID https://scholar.google.com/citations?user=YPrCZXUAAAAJ&hl=en&oi=ao
Scholars Awarded

Sl. No Name Photo Current Status
1 Sayan Chowdhury

Ongoing

2 Soumita Paul

Ongoing

3 Kasturi Roy

Awarded

Current Openings
Students with own fellowship are encouraged to apply.

Research Highlights/Photo gallery