Department of Engineering & Technological Studies (Formerly University Science Instrumentation Centre or USIC) was established in the year 1978 by the University Grants Commission (UGC). With an aim at promoting the Centre and to diversify its activity, the UGC subsequently upgraded it to Level-III, the highest level of an USIC, during its 8th plan period. USIC of University of Kalyani was the only USIC in the Eastern region of the country, which had been upgraded to Level-III by the UGC. As a condition of upgradation, a One-year (Two semesters) Post-Graduate Diploma in Instrumentation (PGDI) course was started from the 1992-1993 academic session. The course was aimed at imparting a job-oriented training programme to Honours Graduates in Physical Sciences. Later to enhance the utility of the course the University upgraded the course to Two-years' (Four semesters) Post-Graduate Diploma in Instrumentation, so that the students can do better in the job market
As per the advice and the approval given by the All India Council of Technical Education (AICTE) in 1999, University of Kalyani introduced Two 4-year B. Tech courses in— (i) Electronics and Instrumentation Engineering and (ii) Information Technology at USIC from the academic session 1999-2000 with the intake from WBJEE. In 2005 USIC obtained the approval of AICTE for M. Tech. course in Communication Engineering, though the course started in 2010-2011 academic session. The Ph.D. curricula in several field of Engineering were also started at USIC from the same academic session, as per UGC guideline. In 2022, the department obtained the approval of AICTE to start a 4-year B. Tech course in Electronics and Communication Engineering and a 2-year M. Tech. course in Information Technology.