Prof. (Dr.) Angshuman Bagchi

Prof. (Dr.) Angshuman Bagchi

Prof. (Dr.) Angshuman Bagchi

Prof. (Dr.) Angshuman Bagchi

Department: Department of Biochemistry and Biophysics
Phone Number: 9051948843
Institutional E-Mail: angshu@klyuniv.ac.in
Web URL: https://www.researchgate.net/profile/Angshuman-Bagchi
Educational Qualifications:

PhD in Computational Biology and Bioinformatics from Bose Institute, P-1/12, CIT Scheme VIIM, Kankurgachi, Kolkata- 700 054

Took part in the ‘Biostatistics for Physicians: A short Course’ conducted by Indiana University School of Medicine, Indianapolis, IN, USA

Postdoctoral Research Fellow in Center of Computational Biology and Bioinformatics, Department of Medical and Molecular Genetics, Indiana University Purdue University, Indianapolis, IN, USA

Postdoctoral Research Fellow in Buck Institute for Age Research, 8001 Redwood Blvd., Novato, California-94945, USA

Visiting research scientist in Department of Computer Science, Hong Kong Baptist University, Hong Kong

Visiting research scientist in Virologie et Immunologie Moléculaires, Paris Saclay University, UR892, INRA Domaine de Vilvert, 78352 Jouy-en-Josas, France

Awards and Honours (National/International)

RECIPIENT OF THE HENRI DUTROCHET EDUCATION EXCELLENCE AWARD, 2022 in Biochemistry from International Multidisciplinary Research Foundation (IMRF), Registered with Govt. of India NITI Ayog NGO Darpan| ESTD:U/S 35 of 2001, Govt. of A.P. |HQ: Vijaywada, India

RECIPIENT OF THE YOUNG ACHIEVER AWARD-2019 FROM INSTITUTE OF SCHOLARS, Registered Under Ministry of MSME, Govt. of India & ISO 9001:2015 Certified

RECIPIENT OF THE AWARD OF THE PROMISING YOUNG FACULTY FROM UNIVERSITY OF KALYANI, ON 1st NOVEMBER, 2017

RECIPIENT OF YOUNG SCIENTIST AWARD FROM VENUS INTERNATIONAL FOUNDATION
(Regd. Trust in India Vide No. 18 / BK-IV/2015) in a ceremony at Hotel Le Royal Meridien, Chennai on 19th of December, 2015

RECIPIENT OF YOUNG SCIENTIST AWARD FROM UNIVERSITY OF KALYANI, ON 15th. AUGUST, 2014

Research Fellowship to Visit the Research Laboratory of Prof. Anny Slama-Schwok, Virologie et Immunologie Moléculaires INRA UR892, Domaine de Vilvert, 78352 Jouy-en-Josas, France

Research Fellowship to Visit the Research Laboratory of Prof. Hailong Zhu, Hong Kong Baptist University, Hong Kong

NIH fellowship for postdoctoral research work

Travel Fellowship Award by the National Science Foundation, USA in 2008

Fellowship from Department of Biotechnology (DBT), India to pursue Post M.Sc. Advanced Diploma in Bioinformatics, 2001-2002

Recipient of Best Paper Award for the paper titled “Determination of Molecular Structure for Drug Design Using Variable String Length Genetic Algorithm” by Angshuman Bagchi, Sanghamitra Bandyopadhyay and Ujjawal Maulik, in the International Conference on High Performance Computing (HiPC) held during Dec. 18-21, 2003

Collaborative Programs

With Prof. Anny Slama-Schwok, Virologie et Immunologie Moléculaires INRA UR892, Domaine de Vilvert, 78352 Jouy-en-Josas, France in the International Project titled “Advanced Methods for Viral Detection and Anti-viral Screening” funded by International Bio-Asia Project Campus France

Research Area:

Computational Biology and Bioinformatics

Teaching Experience:

1. Bioinformatics
2. General Biochemistry and Biophysics

Administrative Experiences

Coordinator of DBT sponsored Bioinformatics Infrastructural Facility (BIF) Center, University of Kalyani

Head, Department of Biochemistry and Biophysics, University of Kalyani

List of Publications(Peer-Reviewed)

Some representative publications:
Year 2022 (till date)
Omeprazole prevents stress induced gastric ulcer by direct inhibition of MMP-2/TIMP-3 interactions
Deep Sankar Rudra, Uttam Pal, Nilkanta Chowdhury, Nakul Chandra Maiti, Angshuman Bagchi , Snehasikta Swarnakar
Free Radical Biology and Medicine (I.F: 7.376), 2022 Mar;181:221-234. doi: 10.1016/j.freeradbiomed.2022.02.007. Epub 2022 Feb 10. ISSN: 0891-5849 (print); 1873-4596 (web)

Year 2021

Identification of the binding interactions of some novel antiviral compounds against Nsp1 protein from SARS-CoV-2 (COVID-19) through high throughput screening
Nilkanta Chowdhury, and Angshuman Bagchi (Corresponding author)
J Biomol Struct Dyn. (I.F: 3.392) 2021 Feb 22:1-8. doi: 10.1080/07391102.2021.1887763. PMID: 33612076; 1538-0254 (Online) 0739-1102 (print)

Mutational Impact on “in-Between-Ring” (IBR) Domain of PARKIN on Protein Stability and Function.
Sima Biswas, and Angshuman Bagchi (Corresponding author)
Appl Biochem Biotechnol. (I.F: 2.926) 2021 Jan 20. doi: 10.1007/s12010-021-03491-2. Online ahead of print. PMID: 33471285, ISSN: 1559-0291(Online), 0273-2289 (Print)

Elucidation of the hetero-dimeric binding activity of LasR and RhlR proteins with the promoter DNA and the role of a specific Phe residue during the biosynthesis of HCN synthase from opportunistic pathogen Pseudomonas aeruginosa.
Nilkanta Chowdhury, and Angshuman Bagchi (Corresponding author)
Journal of Molecular Modeling (I.F: 1.81). 2021 Feb 8; 27(3):76. doi: 10.1007/s00894-021-04701-8. PMID: 33555486. ISSN: 1610-2940 (print version), 0948-5023 (electronic version)

Engineered bio-inspired multifunctional peptide and protein based therapeutic biomolecules for better wound care
Paramita Gayen , Somnath Jan, Nilkanta Chowdhury , Snehasish Ghosh , Monjuri Hembram, Angshuman Bagchi (Corresponding author), Rituparna Sinha Roy
Chem Asian J. (I.F: 4.568) 2021 Dec 13;16(24):4018-4036. doi: 10.1002/asia.202101022. Epub 2021 Nov 8. PMID: 34643055. ISSN: 1861-4728 (print); 1861-471X (web)

Year2020

INVITED ARTICLE
Latest trends in structure based drug design with protein targets
Angshuman Bagchi
Adv Protein Chem Struct Biol. (IF: 10.2) 2020; 121:1-23. doi: 10.1016/bs.apcsb.2019.11.008. Epub 2019 Dec 18.PMID: 32312418; ISSN:1876-1623

Unusual nature of long non-coding RNAs coding for “unusual peptides”
Angshuman Bagchi
Gene (I.F: 2.319), Volume 729, 1 March 2020, 144298, ISSN: 0378-1119

Protein dynamics and molecular motions study in relation to molecular interaction between proteins from sulfur oxidizing proteobacteria Allochromatium vinosum
Semanti Ghosh and Angshuman Bagchi (Corresponding author)
J Biomol Struct Dyn. (I.F: 3.31) 2020 May 6:1-17. doi: 10.1080/07391102.2020.1754914. PMID: 32276557

Repurposed drugs and neutraceuticals targeting envelope protein: A possible therapeutic strategy against COVID-19.
Gourab Das, Troyi Das, Nilkanta Chowdhury, Durbadal Chatterjee, Angshuman Bagchi (Corresponding author), Zhumur Ghosh
Genomics (I.F: 6.205) 2020 Nov 13; 113(1):1129-40. doi: 10.1016/j.ygeno.2020.11.009. Online ahead of print. PMID: 33189776, ISSN: 0888-7543

Prediction of the differentially expressed circRNAs to decipher their roles in the onset of human colorectal cancers.
Rjabrata Bhuyan and Angshuman Bagchi (Corresponding author)
Gene (I.F: 3.688)2020 Dec 15; 762:145035. doi: 10.1016/j.gene.2020.145035. Epub 2020 Aug 8. PMID: 32777531, ISSN: 0378-1119

Design, synthesis and biological evaluation of vortioxetine derivatives as new COX-1/2 inhibitors in human monocytes.
Talmon M, Chaudhari RD, Suryavanshi H, Chowdhury N, Quaregna M, Pin A, Bagchi A, Biswas G, Fresu LG.
Bioorg Med Chem. (I.F: 2.572) 2020 Dec 1;28(23):115760. doi: 10.1016/j.bmc.2020.115760. Epub 2020 Sep 11.PMID: 32992247, ISSN: 0960-894X

Year2019

Structural study to analyze the DNA binding properties of DsrC protein from dsr operon of sulfur oxidizing bacterium Allochromatium vinosum
Semanti Ghosh and Angshuman Bagchi (Corresponding author)
Journal of Molecular Modeling (I.F: 1.425), 2019 Feb 23; 25(3):74. doi: 10.1007/s00894-019-3945-3.ISSN: 1610-2940 (print version), 0948-5023 (electronic version)

Dimerization ability, denaturation mechanism, and the stability of a staphylococcal phage repressor and its two domains
Anindya Biswas, Semanti Ghosh, Debabrata Sinha, Anindya Dutta, Soham Seal, Angshuman Bagchi (Corresponding author), Subrata Sau
International Journal of Biological Macromolecule (I.F: 3.671), 2019 Mar 1; 124:903-914. doi: 10.1016/j.ijbiomac.2018.11.263. Epub 2018 Dec 2. ISSN: 0141-8130 (print version), 1879-0003 (electronic version)

Structural analysis of the effects of mutations in Ubl domain of PARKIN leading to Parkinson’s disease.
Sima Biswas, Riya Roy, Ria Biswas and Angshuman Bagchi (Corresponding author)
Gene (I.F: 2.319) 2019 Oct 21:144186. doi: 10.1016/j.gene.2019.144186. [Epub ahead of print], PMID: 31647998

Structure based virtual screening of natural products to disrupt the structural integrity of TRAF6 C-terminal domain homotrimer
Ria Biswas, Nilkanta Chowdhury, Sima Biswas, Riya Roy and Angshuman Bagchi (Equal Contribution with Ria Biswas and Nilkanta Chowdhury and Corresponding author)
Journal of Molecular Graphics and Modelling (I.F: 1.885) 2019 Dec; 93:107428. doi: 10.1016/j.jmgm.2019.08.005. Epub 2019 Aug 29.ISSN: 1093-3263

Removal of an atypical region from a staphylococcal cyclophilin affects its structure, function, stability, and shape.
Seal S, Chowdhury N, Biswas R, Chakraborty T, Sinha D, Bagchi A (Corresponding author), Sau S.
International Journal of Biological Macromolecule (I.F: 3.671), 2019 Nov 18. pii: S0141-8130(19)34319-3. doi: 10.1016/j.ijbiomac.2019.10.175. ISSN: 0141-8130 (print version), 1879-0003 (electronic version) [Epub ahead of print]

Year 2018

Different roles of circular RNAs with protein coding potentials
Angshuman Bagchi
Biochemical and Biophysical Research Communications (I.F: 2.371), 2018 Jun 12;500(4):907-909. doi: 10.1016/j.bbrc.2018.04.190. Epub 2018 Apr 30. ISSN: 0006-291X

Identification of ligand binding activity and DNA recognition by RhlR protein from opportunistic pathogen Pseudomonas aeruginosa- A molecular dynamics simulation approach
Nilkanta Chowdhury and Angshuman Bagchi (Corresponding author)

Journal of Molecular Recognition (I.F: 2.175), 2018 Jul 2:e2738. doi: 10.1002/jmr.2738. [Epub ahead of print] ISSN: 1099-1352
Alanine substitution mutations in the DNA binding region of a global staphylococcal virulence regulator affect its structure, function, and stability
Sukhendu Mandal, Semanti Ghosh, Debabrata Sinha, Avisek Mahapa, Soumitra Polley, Deeya Saha, Keya Sau, Angshuman Bagchi (Corresponding author), Subrata Sau
International Journal of Biological Macromolecule (I.F: 3.671), ISSN: 0141-8130 (print version), 1879-0003 (electronic version) Mar 12; 113:1221-1232. doi: 10.1016/j.ijbiomac.2018.03.045. [Epub ahead of print]

Insight into the molecular mechanism of sulfur oxidation process by Reverse Sulfite Reductase (rSiR) from sulfur oxidizer Allochromatium vinosum
Semanti Ghosh, Angshuman Bagchi (Corresponding author)
Journal of Molecular Modeling (I.F: 1.425), ISSN: 1610-2940 (print version), 0948-5023 (electronic version)
2018 Apr 26;24(5):117. doi: 10.1007/s00894-018-3652-5.

Disease Probability Index (DPI, χ): A new alignment-free scoring method to evaluate the propensities of polypeptide sequences leading to disease onset
Ananya Ali and Angshuman Bagchi (Corresponding author)
BioSystems (I.F: 1.652), 172, 1-8, ISSN: 0303-2647

Books Published / Book Chapters

BOOK:
Introduction to Bioinformatics published from Narosa Publishing House; ISBN: 978-81-8487-632-1
By Angshuman Bagchi

Year 2022 (Till date)

Book Chapter
Molecular Analysis of the involvements of lncRNAs in Cancer Development
Angshuman Bagchi
In: Chakraborti S., Ray B.K., Roychoudhury S. (eds) Handbook of Oxidative Stress in Cancer: Mechanistic Aspects. Springer, Singapore. https://doi.org/10.1007/978-981-15-9411-3_153 [Invited article] by Springer, ISBN 978-981-15-9410-6 (print) ISBN 978-981-15-9411-3 (eBook)

Molecular Insights into the Roles of E3-Ligases in ROS-Mediated Cancer from a Bioinformatics Perspective.
Sima Biswas and Angshuman Bagchi (Corresponding author)
In: Chakraborti S., Ray B.K., Roychoudhury S. (eds) Handbook of Oxidative Stress in Cancer: Mechanistic Aspects. Springer, Singapore. https://doi.org/10.1007/978-981-15-9411-3_152 [Invited article] by Springer, ISBN 978-981-15-9410-6 (print) ISBN 978-981-15-9411-3 (eBook)

Year 2021

Book Chapter

Application of bioinformatics databases in the study of oxidative stress related cancers
Angshuman Bagchi (Corresponding author), Gaurab Kumar Bhagat
In Handbook of Oxidative Stress in Cancer: Therapeutic Aspects [Invited article] by Springer, ISBN 978-981-16-1247-3

A Critical approach in the Analysis of lncRNA characteristics for Cancer Therapy
Angshuman Bagchi (Corresponding author), Gaurab Kumar Bhagat
In Handbook of Oxidative Stress in Cancer: Therapeutic Aspects [Invited article] by Springer, ISBN 978-981-16-1247-3

An overview of in-silico drug discovery-with emphasis on cancer
Sima Biswas, Angshuman Bagchi (Corresponding author)
In Handbook of Oxidative Stress in Cancer: Therapeutic Aspects [Invited article] by Springer, ISBN 978-981-16-1247-3

Application of Data Science and Bioinformatics tools to study long non-coding RNAs linked to neurodegenerative diseases
Aniruddha Biswas and Angshuman Bagchi (Corresponding author)
In Functional Genomics of Mind [Invited article] PUBLISHED BY SARVASUMANÂ ASSOCIATION, India, ISBN 9798715593061

Parkinson’s Disease – An overview of the available methods for treatment
Sima Biswas and Angshuman Bagchi (Corresponding author)
In Functional Genomics of Mind [Invited article] PUBLISHED BY SARVASUMANÂ ASSOCIATION, India, ISBN 9798715593061

Year 2019

Book Chapter
Role of Noncoding RNA in lung cancer
Angshuman Bagchi
In Oxidative stress in lung diseases [Invited article] by Springer, ISBN 978-981-32-9365-6 ISBN 978-981-32-9366-3 (eBook), https://doi.org/10.1007/978-981-32-9366-3

Year 2017

Book Chapter
Structural interactions between H-NS and IHF with DNA
Angshuman Bagchi
In Methodologies and Application Issues of Contemporary Computing Framework. Springer, Singapore; Print ISBN 978-981-13-2344-7; Online ISBN 978-981-13-2345-4

Invited Lecture / Session Chaired

“Overview of Docking” virtual Faculty development program on ‘Molecular Docking and Simulation’ organized by Padmashree Institute of Management and Science, Kommagatta, Kengeri, Bengaluru, Karnataka 560060 on 4th July, 2021

“Overview of Molecular Modelling” virtual Faculty development program on ‘Molecular Docking and Simulation’ organized by Padmashree Institute of Management and Science, Kommagatta, Kengeri, Bengaluru, Karnataka 560060 on 30th June, 2021

“Bioinformatics and National center for Biotechnology Information (NCBI)” webinar on Bioinformatics and protein characterization organized by Padmashree Institute of Management and Science, Kommagatta, Kengeri, Bengaluru, Karnataka 560060 during 6th to 10th July, 2020

“Protein functional sites” webinar on Bioinformatics and protein characterization organized by Padmashree Institute of Management and Science, Kommagatta, Kengeri, Bengaluru, Karnataka 560060 during 6th to 10th July, 2020

“Bioinformatics and it’s applications” in 2 Day’s Online Workshop and Hands-on Training Organized by Maulana Abul Kalam Azad University of Technology, West Bengal, Haringhata Campus, West Bengal, India during 10th to 11th September, 2020

“Prediction of the mechanism of the catalysis of environmental sulfur compounds by dsr operon-A Bioinformatics Approach” in International Webinar on “Catalysis Virtual Summit 2020” organized by Iris Scientific Group, https://irisscientificgroup.com/conferences/catalysis-and-chemical-science/webinar/home/ during 29th to 30th August, 2020.

“Introduction to Biological Sequence Alignment” in “A National Workshop and Hands-on Training on “Computational Biology with Modern Tools” ”, during June 17-21, 2019, Organized by Maulana Abul Kalam Azad University of Technology, West Bengal, Haringhata Campus, West Bengal, India

“Bioinformatics Infrastructure Facility Center- A Central Facility of the University” in “XXVIII Annual Bioinformatics Coordinators Meeting”, during February 03-04, 2017, at ACTREC, TMC, Kharghar, Navi-Mumbai-410210, India

“Structural Bioinformatic study of sulfur compound metabolizing sox operon” in “3rd International Conference on Public Mental Health and Neurosciences ICPMN-2016”, during December 14-15, 2016, at Jain University, Bangalore, India

“Computational Aspects of Bio-molecular Interactions” in “VIM Work in Progress”, on 22nd March, 2016, at Virologie et Immunologie Moléculaires, Paris Saclay University, UR892, INRA Domaine de Vilvert, 78352 Jouy-en-Josas

“Prediction of Protein-protein interactions by machine learning” in “2nd International Conference on Public Mental Health and Neurosciences ICPMN-2015”, during December 9-10, 2015, at Jyoti Nivas College, Bangalore, India

“Insight into Duchenne Muscular Dystrophy from the analyses of the Dystrophin protein and the mutations therein” in “International Conference on Informatics & Integrative Biology”, during December 17-19, 2014, at Bioinformatics Centre, Bose Institute, Kolkata, India

“Structural Bioinformatic Study of Sulfur Compound Metabolizing sox operon”, A five day National Workshop on “Use of Recombinant DNA in Modern Biotechnological Research” during December 17 – 21, 2013, at Biotechnology Department, National Institute of Technology, Durgapur

“Homology modeling of a dimeric repressor protein SoxR and analysis of its dimeric interface” (Tutorial) in DBT Sponsored National Workshop on “To Predict and Model Biological Molecules and System”, during March 16-18, 2011, at Department of Biochemistry and Biophysics, University of Kalyani

“Molecular modeling of protein interactions in the sox operon”, at Pittsburgh Supercomputing Center, Pittsburgh, Pennsylvania, USA on 4th April, 2010

“Prediction of protein-protein interactions”, at Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina, USA on 22nd April, 2009

“Structural biology of sulfur bacteria (Sox)”, at Max Planck Institute for Molecular Genetics – Ihnestraße 73 – 14195 Berlin, on 22nd January, 2008

ORCID ID 0000-0003-4611-4663
Google Scholar ID https://scholar.google.com/citations?hl=en&user=aQ5JQ3UAAAAJ